Herpes zoster - Èpès Zosterhttps://en.wikipedia.org/wiki/Shingles
Zoster (Herpes zoster) se yon maladi viral ki karakterize pa yon gratèl po douloure ak ti anpoul nan yon zòn lokalize. Tipikman gratèl la rive nan yon sèl, bann lajè swa sou bò gòch oswa bò dwat nan kò a oswa figi. De a kat jou anvan gratèl la rive ka gen pikotman oswa doulè lokal nan zòn nan. Sinon, kèk pasyan ka jis gen lafyèv oswa tèt fè mal, oswa santi yo fatige san gratèl la tipik. Gratèl la anjeneral geri nan de a kat semèn; sepandan, gen kèk moun ki devlope doulè nè ki kontinyèl ki ka dire pou mwa oswa ane, yon kondisyon ki rele postherpetic neuralgia (PHN). Nan moun ki gen fonksyon iminitè pòv, gratèl la ka pi gaye. Si gratèl la enplike je a, pèt vizyon ka rive. Yo estime ke apeprè yon tyè nan moun soufri Zoster (Herpes zoster) nan kèk pwen nan lavi yo. Pandan ke Zoster (Herpes zoster) pi komen nan mitan moun ki pi gran yo, timoun yo ka pran maladi a tou.

Varisèl (chickenpox), ki rele tou varicella, rezilta nan premye enfeksyon an ak viris la, tipikman rive pandan anfans oswa adolesans. Yon fwa varisèl la geri, viris la ka rete inaktif (andòmi) nan selil nè imen an pou ane oswa dè dekad, apre sa li ka reaktive. Zoster (Herpes zoster) rezilta lè viris varicella andòmi an reaktive. Lè sa a, viris la vwayaje sou kò nè yo nan tèminezon nè ki nan po a, ki pwodui ti anpoul. Pandan yon epidemi Zoster (Herpes zoster), ekspoze a viris varicella yo jwenn nan ti anpoul Zoster (Herpes zoster) ka lakòz varisèl nan yon moun ki poko gen varisèl.

Faktè risk pou reaktivasyon viris andòmi an gen ladan laj fin vye granmoun, fonksyon iminitè pòv, ak varisèl kontrakte anvan 18 mwa. Viris varicella‑zoster pa menm ak viris herpes simplex, byenke tou de fè pati menm fanmi herpesviris.

Vaksen Zoster (Herpes zoster) diminye risk pou Zoster (Herpes zoster) pa 50% a 90%. Li diminye tou pousantaj neuralgia postherpetic, epi, si Zoster (Herpes zoster) rive, gravite li. Si Zoster (Herpes zoster) devlope, medikaman antiviral tankou aciclovir ka diminye gravite a ak dire maladi a si yo kòmanse nan lespas 72 èdtan apre aparans nan gratèl la.

Tretman
Si blesi yo pwopaje rapidman, al wè doktè ou pi vit posib pou tretman antiviral.
Yo mande tou de medikaman antiviral ak medikaman pou neuralgia. Ou ta dwe repoze epi sispann bwè alkòl.
#Acyclovir
#Famciclovir
#Valacyclovir

#Gabapentin
#Pregabalin
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  • Herpes zoster ti boul sou kou a ak zepòl
  • Zostè (Shingles) ― Jou 5; Si tretman an kòmanse, sentòm maladi a anjeneral sispann alantou senk jou pita.
  • Nan ka herpes zoster (herpes zoster) gaye toupatou, si tretman antiviral an reta, pasyan an ka soufri ti anpoul douloure pou yon peryòd pwolonje.
  • Sikatris yo ka parèt apre herpes zoster (herpes zoster), ki ka dire anpil tan, menm si viris varicella‑zoster la (varicella‑zoster virus) disparèt.
  • Si fwon an afekte, li souvan akonpaye pa yon tèt fè mal. Si blesi a te afekte zòn ki ozalantou nen an, li enpòtan pou tcheke si vizyon ou nòmal.
  • Ka sa a demontre distribisyon tipik dèrmatomal nan zona.
  • Shingles (herpes zoster) ― Jou 1
  • Zoster (Shingles) ― Jou 2
  • Zoster (Shingles) Jou6 ― Kwout la ak sikatris yo ka pèsiste pou plis pase yon mwa, byenke blesi a pa pwogrese ankò.
  • Nan etap an reta nan herpes zoster (herpes zoster), kwout ak eritem ka dire pou plis pase yon mwa.
  • Zostè (shingles) ka kite mak menm apre yo fin geri.
  • Zoster (herpes zoster); mak
References Herpes Zoster and Postherpetic Neuralgia: Prevention and Management 29431387
Zona, ki te koze pa reaktivasyon viris varicella‑zoster (varicella‑zoster virus) ki responsab varicella la, afekte anviwon 1 milyon moun chak ane nan peyi Etazini, ak yon risk pou tout lavi 30%. Moun ki gen sistèm iminitè febli yo siyifikativman plis tandans devlope zona, ak sentòm tipikman kòmanse ak malèz, maltèt, ak yon lafyèv ki pa twò grav, ki te swiv pa sansasyon po etranj kèk jou anvan aparans nan yon gratèl. Gratèl sa a, anjeneral parèt nan yon zòn espesifik nan kò a, pwogrese soti nan ti anpoul klè nan maleng kwout sou yon semèn a dis jou. Tretman rapid ak medikaman antiviral (acyclovir, valacyclovir, oswa famciclovir) nan lespas 72 èdtan apre kòmansman gratèl la enpòtan anpil. Neuralji postherpetic, yon konplikasyon komen ki karakterize pa doulè pwolonje nan zòn ki afekte a, afekte apeprè youn nan senk pasyan epi li mande pou jesyon kontinyèl ak medikaman tankou gabapentin, pregabalin, oswa sèten antidepresan, ansanm ak ajan topik tankou lidokayin oswa capsaicin. Yo rekòmande vaksinasyon kont viris varicella‑zoster (varicella‑zoster virus) la pou adilt ki gen laj 50 an oswa pi wo a pou diminye risk pou yo gen zona.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
 Epidemiology, treatment and prevention of herpes zoster: A comprehensive review 29516900
Herpes zoster gen tandans rive pi souvan nan moun ki gen laj 50 an oswa plis, moun ki gen sistèm iminitè febli, ak moun ki pran medikaman imunosuppressant. Li deklanche pa reyaktivasyon viris varicella‑zoster (varicella‑zoster virus) la, menm viris ki lakòz varisèl la. Sentòm tankou lafyèv, doulè, ak gratèl souvan anvan aparans nan gratèl la karakteristik. Konplikasyon ki pi komen se neuralji pòs‑herpes zoster (postherpetic neuralgia), ki se doulè nè ki pèsistan apre gratèl la efase. Faktè risk ak konplikasyon ki asosye ak herpes zoster (herpes zoster) yo varye selon laj, sante iminitè, ak tan inisyasyon tretman an. Vaksinasyon pou moun ki gen laj 60 ak pi wo yo te montre siyifikativman diminye ensidan an nan herpes zoster (herpes zoster) ak neuralji pòs‑herpes zoster (postherpetic neuralgia). Kòmanse medikaman antiviral ak soulaje doulè nan lespas 72 èdtan apre aparisyon gratèl la ka diminye gravite ak konplikasyon herpes zoster (herpes zoster) ak neuralji pòs‑herpes zoster (postherpetic neuralgia).
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
 Prevention of Herpes Zoster: A Focus on the Effectiveness and Safety of Herpes Zoster Vaccines 36560671 
NIH
Esè klinik yo anvan apwobasyon endike ke vaksen zoster vivan travay alantou 50 a 70 %, pandan y ap vaksen rekombinan fè pi byen, sòti nan 90 a 97 %. Nan syans reyèl yo, yo sipòte rezilta esè yo, ki montre ke vaksen zoster vivan se apeprè 46 % efikas, pandan vaksen rekombinan se alantou 85 %.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.